The Office for Human Research Protections (OHRP) provides leadership in the protection of the rights, welfare, and wellbeing of human subjects involved in research conducted or supported by the U.S. Department of Health and Human Services (HHS). OHRP is part of the Office of the Assistant Secretary for Health in the Office of the Secretary of HHS.
OHRP provides clarification and guidance, develops educational programs and materials, maintains regulatory oversight, and provides advice on ethical and regulatory issues in biomedical and behavioral research. OHRP also supports the Secretary's Advisory Committee on Human Research Protections (SACHRP), which advises the HHS Secretary on issues related to protecting human subjects in research.
Thursday, August 26, 1-3 PM EDT. Free access. No registration
Regulations, Policy & Guidance
Learn about federal regulations that protect human subjects in research and find policy and guidance materials related to the regulations.
Compliance & Reporting
Find out how OHRP exercises regulatory oversight and responds to reports of incidents in HHS-supported research.
Find out more about the Secretary’s Advisory Committee on Human Research Protections.
Learn how OHRP promotes ethical conduct and regulatory compliance in HHS-supported research studies conducted outside the United States.
OHRP COVID-19 Information
Read OHRP’s COVID-19 guidance, watch OHRP’s videocast on the guidance and find other information on the HHS COVID-19 response.
Final Rule Revising the Common Rule
About Research Participation
Find informative materials for members of the public who are considering research participation or interested in the topic.
Get a Web Button
Download and post a web button on your website to link to our About Research Participation resources for the general public.