Update or Renew an IRB Registration

To obtain a submission number you will need to know three things:

1. Your IORG number.
2. Your organization’s Head Official’s s last name, as of the most recent registration.
3. Last name of your first IRB's Chairperson, as of the most recent registration.

Please follow the instructions below:

1. Visit http://ohrp.cit.nih.gov/efile/IrbRnwStart.aspx
2. Scroll down to the bottom of the screen and click on ‘I need a submission number” Enter
   1. IORG number,
   2. The last name of the IORG head official/senior officer
   3. The last name of one of the IRB chairs
   4. Your e-mail address,
   5. A password with a mix of upper and lower case letters and numbers or special characters, and
   6. A password hint that cannot be the same as the password.
3. Click on the “Submit” button
4. Once you receive the submission number:
   1. Repeat step 1 above.
   2. Then scroll down to the bottom of the screen and click “I have a submission number”.
   3. Enter the submission number and the password
   4. Click on the “Submit” button
5. Your organization’s registration records should then be presented so that you can update/renew the registration.
6. Follow the step-by-step instructions for updating the IORG IRB registration information.

A registration and any update/renewal is good for three years from the date of acceptance by OHRP and can be updated/renewed at any time.

A registration update must be made:

1. Within 90 days after changes regarding the contact person who provided the IRB registration information or the IRB chairperson,
2. To register any additional IRB before it is designated under an FWA and reviews research conducted or supported by HHS.
3. If an FDA-regulated IRB decides to review additional types of FDA-regulated products (e.g., to review device studies if it only reviewed drug studies previously) or to discontinue reviewing clinical investigations regulated by FDA, it must report this within 30 days of the change.

An institution’s or organization’s decision to disband a registered IRB that it is operating must be reported in writing within 30 days after permanent cessation of the IRB's review of HHS-conducted or –supported research.

An institution or organization should update its IRB registration within 90 days of a change in the membership roster if that IRB is designated under an FWA.

A short tutorial on the IRB-Registration process is located at: https://www.youtube.com/watch?v=57EQt8xtwsc